ABSTRACT
Castleman's disease, giant lymph node hyperplasia, is a kind of benign lymphoproliferative disease with gentle behavior. Its etiology and prevalence are unclear. This rare disease is usually found in mediastinal area asymptomatically and incidentally. It is also rare to see this tumor in the retroperitoneum. In this study, we have introduced a 34-year-old woman who referred just with occasional abdominal pain caused by compressive symptoms. Laboratory findings only reported microcytic anemia [MCH: 18.5, MCV: 63, Hemoglobin 10.2 g/dl]. Chest and abdominal X-ray imaging showed no remarkable point. In abdominal ultrasonography, a solid and firm tumor with 12.2x5.3x6.6 cm was reported in patient's retroperitoneum. Patient's surgery was done and the tumor [covered by a fibrous thick capsule, with no bizarre appearance and bleeding] was completely removed. Pathologic examination indicated a Castleman's tumor, type of unicentric and hyaline-vascular. This item had been one of the rare reported items of Castleman's disease in the retroperitoneal space
ABSTRACT
Leptin is one of the possible mediators of ethanol intake. On the other hand, the concentration of total plasma homocysteine [Hcy] is a well-established indicator for the risk of cardiovascular disease, and seems to be related to ethanol consumption. So, the aim of the present study was to investigate the effect of acute [70%] and chronic [10%] exposure to evaporated ethanol on: 1-brain leptin and Hcy concentration on the 15th day of embryonic development of chick. 2- brain leptin and Hcy concentration immediately after hatch of chick and 3- serum leptin concentration immediately after hatch of chick. In this experimental study sixty fertilized eggs were used. Eggs were divided into control; acute exposure to ethanol and chronic exposure to ethanol. Hcy was measured by using enzyme-linked assay, and leptin was measured with the chick leptin radioimmunoassay kit. Data showed brain Hcy concentration on the 15th day of embryonic stage of chicken that acute and chronic exposure to ethanol significantly [p<0.05] decreased, but did not have any effect on brain Hcy concentration immediately after hatch in chicken that acute and chronic exposure to ethanol during embryonic stages. Acute and chronic exposure to ethanol during embryonic stages significantly [p<0.05] increased brain leptin on the 15th day of embryonic stage, brain leptin immediately after hatch of chicken and plasma leptin immediately after hatch of chicken. Present results indicated that acute and chronic exposure to ethanol by evaporation in embryonic stage of chicken can change the brain Hcy, brain leptin and serum leptin
ABSTRACT
High-risk pregnancies increase the risk of Intensive Care Unit [ICU] and Neonatal Intensive Care Unit [NICU] admission in mothers and their newborns. In this study, we aimed to identify the association between the recurrence of high-risk pregnancy and mothers' previous experience of having an infant admitted to NICU. We performed a cohort, retrospective study to compare subsequent pregnancy outcomes among 232 control subjects and 200 female cases with a previous experience of having a newborn requiring NICU admission due to intrauterine growth retardation, preeclampsia, preterm birth, premature rupture of membranes, and asphyxia. The information about the prevalence of subsequent high-risk pregnancies was gathered via phone calls. As the results indicated, heparin, progesterone, and aspirin were more frequently administered in the case group during subsequent pregnancies, compared to the control group [P<0.001]. Also, pregnancy-induced hypertension, preeclampsia, preterm labor, and gestational diabetes mellitus were more frequent in the case group, compared to the control group [P<0.05]. There was a positive correlation between recurrent high-risk pregnancy and previous experience of having a newborn requiring NICU admission. As the results indicated, mothers in the case group were at a higher risk for preeclampsia, preterm labor, and gestational diabetes mellitus, compared to the control group. Therefore, earlier diagnosis, prompt treatment, and prevention should be taken into account by physicians
ABSTRACT
High risk pregnancies increase the risk of neonatal mortality and morbidity. In order to identify the influence of pregnancy complications on the period of neonatal stay in Neonatal Intensive Care Units [NICUs], an analysis has been carried out in our center. In a cross-sectional-descriptive analytical study, the data including NICU length of stay was gathered from 526 medical records of neonates. We also assessed their maternal complications such as premature rapture of membranes [PROM], urinary tract infection [UTI], preeclampsia, oligohydramnios, and twin/triplet pregnancy. Finally we analyzed the relation between variables by SPSS statistics software version 19. The level of significance was considered P<0.05. 37 of 526 neonatal medical records were excluded. Of the 489 babies hospitalized in NICU for 1 to 54 days; 28.42% born were preterm, 308 with birth weight <2500 gram and 170 with birth weight between 2500 and 4000 gram. There was a significant relation between length of neonatal NICU stay and maternal PROM [P=0.001], preeclampsia [P=0.01], UTI [P=0.02], multiple gestation [P=0.03], and oligohydramnios[P=0.003]. We found a positive correlation between numbers of gestation and length of NICU stay [P=0.03]. A positive correlation existed between neonatal complication and length of NICU stay [P<0.001]. By increasing maternal health level and prenatal care services, neonatal outcome can be improved and length of stay in NICUs decreased
ABSTRACT
According to some studies, fetal wound in contrast with adult wound heals without scar formation which is probably due to amniotic fluid around the fetus, unique extracellular matrix and the fetal immature immunity. It is supposed that biochemical and physical characteristics of amniotic fluid prepares the conditions for wound healing without scar formation. The goal of this study was to compare the scar diameter of uncomplicated appendectomy by Rocky-Davis incision with scar diameter of cesarean section by Pfanneistiel incision in order to evaluate the effect of amniotic fluid on scar diameter. In this analytic within-patient study all women with uncomplicated appendectomy by Rocky-Davis incision who were pregnant or had history of cesarean in the last 18 months were included [2007-2009]. After 18 months of operation [appendectomy and cesarean], scar diameters were measured in three points [first, middle and end of scar] and the mean was calculated. Then the mean scar diameter of appendectomy was compared with the mean scar diameter of cesarean in each patient. For data analysis we used T-test, Paired T-test, correlation coefficient and regression tests. In this study the effect of weight and height on scar diameter was evaluated. Mean scar diameter of appendectomy was 2.09 +/- 0.677 millimeter and the mean scar diameter of cesarean was 0.467 +/- 0.633 millimeter which was significantly less than appendectomy scar diameter [p=0.008]. It seems that the presence of amniotic fluid in the first hours of healing decreases the future scar diameter